Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479198 | 0.83 | MEN1 (0.56) | MEN1KMT2AHRH1KCNH2 | |
| SCHEMBL9786921 | 0.82 | MEN1 (0.57) | MEN1KMT2AHRH1KCNH2 | |
| SCHEMBL10479170 | 0.80 | KCNH2 (0.47) | MEN1HRH1KCNH2 | |
| SCHEMBL9874231 | 0.78 | MEN1 (0.51) | MEN1KMT2AHRH1KCNH2 | |
| SCHEMBL9873531 | 0.78 | MEN1 (0.51) | MEN1HRH1 | |
| SCHEMBL10479173 | 0.77 | MEN1 (0.57) | MEN1KMT2A | |
| SCHEMBL9873458 | 0.76 | MEN1 (0.51) | MEN1KMT2A | |
| SCHEMBL9874473 | 0.76 | MEN1 (0.51) | MEN1KMT2AHRH1KCNH2 | |
| SCHEMBL9873310 | 0.75 | MEN1 (0.49) | MEN1 | |
| SCHEMBL9873147 | 0.75 | MEN1 (0.51) | MEN1KMT2AHRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806560-A | ANTIHISTAMINES AND ANTISEROTONINE AGENTS | SYNTHELABO (FR) | 1989-02-21 | — | — | US | disclosed |