Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479583 | 1.00 | KMT2A (0.47) | KMT2AMEN1ALDH1A1CYP2D6RAB9A | |
| SCHEMBL10900503 | 0.98 | KMT2A (0.48) | KMT2AMEN1ALDH1A1CYP2D6RAB9A | |
| SCHEMBL10900495 | 0.98 | KMT2A (0.48) | KMT2AMEN1ALDH1A1CYP2D6RAB9A | |
| SCHEMBL10480084 | 0.97 | RAB9A (0.46) | KMT2AMEN1ALDH1A1CYP2D6RAB9A | |
| SCHEMBL10480085 | 0.97 | RAB9A (0.46) | KMT2AMEN1ALDH1A1CYP2D6RAB9A | |
| SCHEMBL9344262 | 0.94 | HRH3 (0.47) | KMT2AMEN1ALDH1A1CYP2D6RAB9A | |
| SCHEMBL9344249 | 0.94 | HRH3 (0.47) | KMT2AMEN1ALDH1A1CYP2D6RAB9A | |
| SCHEMBL9349601 | 0.94 | HRH3 (0.47) | KMT2AMEN1ALDH1A1CYP2D6RAB9A | |
| SCHEMBL10718126 | 0.94 | KMT2A (0.45) | KMT2AMEN1ALDH1A1CYP2D6RAB9A | |
| SCHEMBL9349588 | 0.94 | HRH3 (0.47) | KMT2AMEN1ALDH1A1CYP2D6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871470-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-10-03 | — | — | US | disclosed |