Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20860726 | 0.73 | CYP2A6 (0.47) | MAPTHTTALDH1A1HPGDNPSR1 | |
| SCHEMBL11753842 | 0.73 | CYP2A6 (0.41) | MAPTALDH1A1MEN1KMT2ACDK2 | |
| SCHEMBL369158 | 0.70 | CYP2A6 (0.38) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10479794 | 0.70 | CYP2A6 (0.38) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL17053161 | 0.68 | CYP2A6 (0.33) | CYP2A6 | |
| SCHEMBL25143012 | 0.66 | NPC1 (0.43) | MAPTSMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL10967877 | 0.66 | ALDH1A1 (0.46) | MAPTSMN1; SMN2HTTALDH1A1MEN1 | |
| SCHEMBL963271 | 0.65 | KMT2A (0.39) | MAPTSMN1; SMN2HTTALDH1A1MEN1 | |
| SCHEMBL6670441 | 0.64 | TYMS (0.45) | MAPTSMN1; SMN2HTTALDH1A1HPGD | |
| SCHEMBL5852752 | 0.63 | HSD17B10 (0.41) | MAPTSMN1; SMN2HTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839365-A | Thienopyridine derivatives useful in treating gastric ulcers | SHINOGI & CO., LTD. (JP) | 1989-06-13 | — | — | US | disclosed |