Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479643 | 0.97 | GRIA2 (0.44) | PTGS2GRIA2CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL9148169 | 0.96 | PTGS2 (0.45) | PTGS2GRIA2CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL10479629 | 0.85 | PTGS2 (0.56) | PTGS2GRIA2CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL10479453 | 0.85 | PDE4A (0.41) | PTGS2GRIA2CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL10479382 | 0.85 | PTGS2 (0.59) | PTGS2GRIA2CYP2C19CYP2C9PTGS1 | |
| SCHEMBL10479492 | 0.83 | PTGS2 (0.54) | PTGS2GRIA2CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL10479634 | 0.82 | PTGS2 (0.43) | PTGS2GRIA2CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL10479605 | 0.82 | PTGS2 (0.59) | PTGS2GRIA2CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL10479802 | 0.82 | PTGS2 (0.59) | PTGS2GRIA2CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL10479454 | 0.80 | MAPT (0.49) | PTGS2GRIA2CYP2C19GAAFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851425-A | Cyclopentapyrazole and tetrahydroindazole compounds and their use as anti-inflammatory and anti-allergic agents | THE UPJOHN COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| WO-1986007357-A3 | CYCLOPENTAPYRAZOLE AND TETRAHYDROINDAZOLE COMPOUNDS | THE UPJOHN COMPANY (US) | 1987-04-23 | — | — | WO | disclosed |