Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2393157 | 0.85 | LOXL2 (0.53) | LOXL2AGXTFLT3ESR1ESR2 | |
| SCHEMBL7140949 | 0.78 | LOXL2 (0.56) | LOXL2AGXTFLT3ESR1ESR2 | |
| SCHEMBL8783399 | 0.75 | HDAC1 (0.60) | NPC1MEN1TSHRRAB9AKMT2A | |
| SCHEMBL436458 | 0.75 | CYP2A6 (0.51) | LOXL2AGXTALOX5 | |
| SCHEMBL30886917 | 0.74 | SMN1; SMN2 (0.57) | LOXL2AGXTMAPK1ALDH1A1HPGD | |
| SCHEMBL10368235 | 0.74 | LOXL2 (0.55) | LOXL2AGXTFLT3ESR1ESR2 | |
| SCHEMBL5986670 | 0.74 | LOXL2 (0.59) | LOXL2AGXTFLT3ESR1ESR2 | |
| SCHEMBL1176465 | 0.73 | LOXL2 (0.50) | LOXL2AGXTFLT3ESR1ESR2 | |
| SCHEMBL7248298 | 0.73 | LOXL2 (0.53) | LOXL2AGXTFLT3ESR1ESR2 | |
| SCHEMBL6243293 | 0.72 | LOXL2 (0.66) | LOXL2AGXTFLT3ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822809-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1989-04-18 | — | — | US | disclosed |