Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297518 | 0.90 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1CA1CA2 | |
| Hydrochloric Acid SCHEMBL10645058 | 0.88 | ALDH1A1 (0.46) | ALDH1A1CA1CA2CA9CA12 | |
| Acetone SCHEMBL28985558 | 0.85 | SMN1; SMN2 (0.41) | GAAALDH1A1CA1CA2CA9 | |
| SCHEMBL8885093 | 0.84 | GAA (0.67) | GAAALDH1A1BCHEACHEKMT2A | |
| SCHEMBL1586 | 0.83 | GAA (0.62) | GAAALDH1A1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL31231738 | 0.83 | GAA (0.62) | GAAALDH1A1KMT2ACYP3A4CYP2C9 | |
| Methylene Chloride SCHEMBL7156245 | 0.81 | GAA (0.54) | GAAALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL6621808 | 0.81 | GAA (0.59) | GAAALDH1A1KMT2ACYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL2833772 | 0.81 | GAA (0.59) | GAAALDH1A1KMT2ACYP3A4CYP2C9 | |
| Water SCHEMBL6162445 | 0.81 | GAA (0.59) | GAAALDH1A1KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989008650-A1 | THIAZOLIDINEDIONE HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1989-09-21 | — | — | WO | disclosed |