Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10480938 | 1.00 | GLO1 (0.63) | GLO1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL10375508 | 0.90 | GLO1 (0.79) | GLO1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL10376715 | 0.90 | GLO1 (0.79) | GLO1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL11733751 | 0.89 | GLO1 (0.61) | GLO1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL9727514 | 0.88 | GLO1 (0.64) | GLO1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL9727518 | 0.88 | GLO1 (0.64) | GLO1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL7265045 | 0.88 | GLO1 (0.73) | GLO1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL30296654 | 0.85 | GLO1 (0.79) | GLO1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL30477011 | 0.85 | GLO1 (0.79) | GLO1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL9667966 | 0.85 | GLO1 (0.79) | GLO1LMNAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4798840-A | Coronary-active fluorine-containing 1,4-dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-17 | — | — | US | disclosed |