Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27606978 | 0.95 | — | — | |
| Phosphoric Acid SCHEMBL1116237 | 0.94 | — | — | |
| Phosphoric Acid SCHEMBL2014213 | 0.89 | — | — | |
| Phosphoric Acid SCHEMBL7197372 | 0.89 | — | — | |
| Phosphoric Acid SCHEMBL2181873 | 0.89 | SLC34A1 (0.64) | SLC34A1LMNACA2KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL25171736 | 0.89 | — | — | |
| Phosphoric Acid SCHEMBL7077939 | 0.89 | — | — | |
| Phosphoric Acid SCHEMBL21815630 | 0.89 | SLC34A1 (0.64) | SLC34A1LMNACA2KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL22436333 | 0.89 | SLC34A1 (0.64) | SLC34A1LMNACA2KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL25171737 | 0.89 | SLC34A1 (0.64) | SLC34A1LMNACA2KDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154113-A1 | METHOD FOR PRODUCING MODIFIED POLYDIENES (VARIANTS) | ПУБЛИЧНОЕ АКЦИОНЕРНОЕ ОБЩЕСТВО "СИБУР ХОЛДИНГ" (ПАО "СИБУР ХОЛДИНГ") | 2021-08-05 | — | — | WO | disclosed |
| US-4827037-A | Quality of catalytically prepared polyalkylene polyamines | UNION CARBIDE CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0138050-B1 | POLYALKYLENE POLYAMINES FROM ALKANOLAMINE AND AMMONIA OR AMINES USING GROUP IIIB METAL ACID PHOSPHATE CATALYSTS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1988-06-01 | — | — | EP | disclosed |
| EP-0131958-B1 | PRODUCTION OF NON CYCLIC POLYALKYLENE POLYAMINES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-12-30 | — | — | EP | disclosed |
| EP-0200250-A2 | Improving the quality of catalytically prepared polyalkylene polyamines | UNION CARBIDE CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |
| EP-0200251-A2 | Use of pressure to control the noncyclics/cyclics ration of polyalkylene amines | UNION CARBIDE CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |
| EP-0197613-A2 | Water addition to enhance phosphoric acid salt catalyst activity | UNION CARBIDE CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0197611-A2 | Conversion of oxygen-containing polyamines | UNION CARBIDE CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0197612-A2 | Interchangeable process scheme | UNION CARBIDE CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |
| US-4605770-A | Noncyclic polyalkylene polyamines by the reaction of an alkanolamine compound and an alkyleneamine compound in the presence of a Group IIA or Group IIIB metal acid phosphate catalyst | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-08-12 | — | — | US | disclosed |
| US-4578517-A | Polyalkylene polyamines from alkanolamine and ammonia or amines using group IIIB metal acid phosphate catalysts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-03-25 | — | — | US | disclosed |
| EP-0149811-A2 | Production of noncyclic polyalkylene polyamines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-07-31 | — | — | EP | disclosed |
| EP-0138050-A2 | Polyalkylene polyamines from alkanolamine and ammonia or amines using group IIIB metal acid phosphate catalysts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0131958-A1 | Production of non cyclic polyalkylene polyamines | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-01-23 | — | — | EP | disclosed |
| US-4463193-A | REACTION OF AN ALKANOLAMINE WITH AN ALKYLENEAMINE AND AMMONIA OR A PRIMARY OR SECONDARY AMINE | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1984-07-31 | — | — | US | disclosed |