Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.34 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481416 | 0.91 | ALDH1A1 (0.46) | ALDH1A1MEN1GAAKMT2AHPRT1 | |
| SCHEMBL9583508 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MEN1GAAKMT2ADGKA | |
| SCHEMBL9584112 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MEN1GAAKMT2ADGKA | |
| SCHEMBL9583018 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MEN1GAAKMT2AP2RY10 | |
| SCHEMBL10814251 | 0.84 | HPRT1 (0.43) | ALDH1A1MEN1GAAKMT2AHPRT1 | |
| SCHEMBL10814414 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MEN1GAAKMT2AHPRT1 | |
| SCHEMBL9463654 | 0.80 | HPRT1 (0.39) | ALDH1A1MEN1GAAKMT2AHPRT1 | |
| SCHEMBL9463583 | 0.80 | HPRT1 (0.39) | ALDH1A1MEN1GAAKMT2AHPRT1 | |
| SCHEMBL9465419 | 0.80 | HPRT1 (0.39) | ALDH1A1MEN1GAAKMT2AHPRT1 | |
| SCHEMBL9583951 | 0.80 | HPRT1 (0.40) | ALDH1A1MEN1GAAKMT2AHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816447-A | HERPES VIRUS | MERCK & CO., INC. (US) | 1989-03-28 | — | — | US | disclosed |
| EP-0074306-B1 | ANTI-VIRAL GUANINE DERIVATIVES | MERCK & CO. INC. (US) | 1988-06-01 | — | — | EP | disclosed |
| EP-0165164-A1 | Anti-viral compounds, their preparation and anti-viral compositions | MERCK & CO. INC. (US) | 1985-12-18 | — | — | EP | disclosed |
| EP-0074306-A2 | Anti-viral guanine derivatives | MERCK & CO. INC. (US) | 1983-03-16 | — | — | EP | disclosed |