⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10482114 | 1.00 | — | — | |
| SCHEMBL1576920 | 0.92 | — | — | |
| SCHEMBL23000713 | 0.80 | — | — | |
| SCHEMBL15466551 | 0.75 | — | — | |
| SCHEMBL11315963 | 0.73 | ALDH1A1 (0.34) | — | |
| SCHEMBL11315965 | 0.73 | ALDH1A1 (0.34) | — | |
| SCHEMBL5907723 | 0.69 | — | — | |
| SCHEMBL5907726 | 0.69 | — | — | |
| SCHEMBL28904 | 0.68 | PSMB5 (0.33) | — | |
| SCHEMBL317737 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347097-B1 | SUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS MODULATORS OF THE KINASES JAK, FLT3 AND AURORA | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-02-24 | — | — | EP | claimed |
| EP-3347097-B1 | SUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS MODULATORS OF THE KINASES JAK, FLT3 AND AURORA | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-02-24 | — | — | EP | disclosed |
| EP-3347097-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-18 | — | — | EP | disclosed |
| WO-2017044434-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-03-16 | — | — | WO | disclosed |
| CN-1163549-C | Azo dye, and its preparing process and use | �������⻯ѧƷ�ع�����˾ | 2004-08-25 | — | — | CN | disclosed |
| CN-1266869-A | Azo dye, and its preparing process and use | CIBA SC HOLDING AG (CH) | 2000-09-20 | — | — | CN | disclosed |
| EP-0344602-A1 | 6-Substituted 4-hydroxy-tetrahydro-pyran-2-one derivatives, process for their production, pharmaceutical preparations based on these compounds | Roche Diagnostics GmbH (DE) | 1989-12-06 | — | — | EP | disclosed |