Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609739 | 0.85 | TDP1 (0.56) | TDP1TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29508624 | 0.84 | KMT2A (0.63) | TDP1KMT2AMEN1F2PRSS1 | |
| SCHEMBL1317710 | 0.84 | KMT2A (0.63) | TDP1KMT2AMEN1F2PRSS1 | |
| SCHEMBL10654745 | 0.83 | KMT2A (0.49) | TDP1TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9356245 | 0.81 | TDP1 (0.64) | TDP1TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10700952 | 0.81 | TDP1 (0.64) | TDP1TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9574478 | 0.80 | HTR6 (0.35) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL6616509 | 0.79 | TDP1 (0.62) | TDP1TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6616502 | 0.79 | TDP1 (0.62) | TDP1TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1807309 | 0.79 | TDP1 (0.62) | TDP1TSHRSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310944-A2 | Bisoxethylsulfonylmethyl anilines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-12 | — | — | EP | disclosed |