SCHEMBL10482199

SCHEMBL10482199

COc1cc(OC)nc(Oc2cccnc2C(=O)OC(C)C)n1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CTSA P10619 2/20 0.52
NPSR1 Q6W5P4 2/20 0.47
CYP1A2 P05177 3/20 0.46
CYP2C9 P11712 3/20 0.46
CYP2C19 P33261 3/20 0.46
CYP3A4 P08684 2/20 0.46
ALDH1A1 P00352 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ATM Q13315 1/20 0.46
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL9694122 0.99 CTSA (0.52) CTSANPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL10774639 0.91 CTSA (0.52) CTSANPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL731243 0.87 ALDH1A1 (0.56) CTSANPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL10778988 0.84 CTSA (0.54) CTSANPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL7814676 0.83 CTSA (0.57) CTSANPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL7846224 0.83 CTSA (0.55) CTSANPSR1CYP1A2CYP2C9CYP2C19
Isopropylamine SCHEMBL9694115 0.83 CTSA (0.55) CTSANPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL9046952 0.83 CTSA (0.50) CTSANPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL9692224 0.82 CTSA (0.56) CTSANPSR1CYP1A2CYP2C9CYP2C19
SCHEMBL9694228 0.82 CTSA (0.56) CTSANPSR1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4832729-A Picolinic acid derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-05-23 US claimed