Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.49 |
| ▸ | KYNU | Q16719 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10482873 | 1.00 | MME (0.56) | MMEECE1CTSLCTSSCTRB1 | |
| SCHEMBL10482881 | 1.00 | MME (0.56) | MMEECE1CTSLCTSSCTRB1 | |
| SCHEMBL28414503 | 0.86 | CTSL (0.61) | MMEECE1CTSLCTSSCTRB1 | |
| SCHEMBL19021627 | 0.86 | CTSL (0.61) | MMEECE1CTSLCTSSCTRB1 | |
| SCHEMBL7716999 | 0.85 | ECE1 (0.60) | MMEECE1CTSLCTSSPRTN3 | |
| SCHEMBL5415836 | 0.85 | CETP (0.53) | MMEECE1CTSLCTSSCTRB1 | |
| SCHEMBL31479939 | 0.85 | CTSL (0.60) | MMEECE1CTSLCTSSCTRB1 | |
| SCHEMBL19519899 | 0.85 | CTSL (0.60) | MMEECE1CTSLCTSSCTRB1 | |
| SCHEMBL8352939 | 0.85 | CTSL (0.60) | MMEECE1CTSLCTSSCTRB1 | |
| Bromide SCHEMBL1436853 | 0.84 | ECE1 (0.59) | MMEECE1CTSLCTSSPRTN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4849414-A | HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0249445-A2 | Substituted aminoalkanoylaminoalkyl phosphonate angiotensin converting enzyme inhibitors | E.R. Squibb & Sons, Inc. (US) | 1987-12-16 | — | — | EP | disclosed |