Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483690 | 0.92 | ELANE (1.00) | ELANEPOLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL3079124 | 0.85 | ELANE (0.73) | ELANEPOLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL12642500 | 0.85 | ELANE (0.73) | ELANEPOLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL525974 | 0.85 | ELANE (0.73) | ELANEPOLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL3193624 | 0.85 | ELANE (0.73) | ELANEPOLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL12370828 | 0.85 | ELANE (0.73) | ELANEPOLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL28581457 | 0.85 | ELANE (0.73) | ELANEPOLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL28585415 | 0.85 | ELANE (0.73) | ELANEPOLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL28605208 | 0.85 | ELANE (0.73) | ELANEPOLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL28598290 | 0.85 | ELANE (0.73) | ELANEPOLBKMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121331-A | Phenoxy aromatic acid compound with cyclopropyl and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-07-16 | — | — | CN | claimed |
| US-4801610-A | ANTIINFLAMMATORY | G. D. SEARLE & CO. (US) | 1989-01-31 | — | — | US | disclosed |
| US-4683241-A | ANTIINFLAMMATORY AGENTS ENZYME INHIBITORS | G. D. SEARLE & CO. (US) | 1987-07-28 | — | — | US | disclosed |