Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 6/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484081 | 0.96 | SLC2A1 (0.41) | SLC2A1MMP13MMP2NPBWR1KMT2A | |
| SCHEMBL10348679 | 0.90 | MMP13 (0.43) | SLC2A1MMP13MMP2KMT2AMMP1 | |
| SCHEMBL10484143 | 0.89 | SLC2A1 (0.50) | SLC2A1MMP13MMP2CYP1A2CYP2D6 | |
| SCHEMBL8673861 | 0.87 | SLC2A1 (0.50) | SLC2A1CYP2C19CYP3A4NPBWR1KMT2A | |
| SCHEMBL9778854 | 0.86 | SLC2A1 (0.39) | SLC2A1MMP13MMP2NPBWR1KMT2A | |
| SCHEMBL9779056 | 0.85 | SLC2A1 (0.41) | SLC2A1MMP13MMP2NPBWR1KMT2A | |
| SCHEMBL10484338 | 0.85 | CYP1A2 (0.42) | SLC2A1MMP13MMP2CYP1A2CYP2D6 | |
| SCHEMBL10484078 | 0.84 | SLC2A1 (0.50) | SLC2A1MMP13MMP2CYP1A2CYP2D6 | |
| SCHEMBL10484383 | 0.84 | SLC2A1 (0.40) | SLC2A1CYP1A2HIF1ANPBWR1KMT2A | |
| SCHEMBL9465883 | 0.83 | SLC2A1 (0.46) | SLC2A1CYP2C19CYP3A4KMT2AMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829090-A | SECONDARY AMINES, ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1989-05-09 | — | — | US | disclosed |
| US-4810727-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0125701-B1 | POLYCYCLIC AROMATIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-08-03 | — | — | EP | disclosed |
| US-4719048-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719046-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0125701-A2 | Polycyclic aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-21 | — | — | EP | disclosed |