MMP13 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL24550	1.00	20/20
SCHEMBL24724	1.00	20/20
SCHEMBL25304	1.00	20/20
SCHEMBL25363	1.00	20/20
SCHEMBL74337	1.00	20/20
SCHEMBL75032	1.00	20/20
SCHEMBL75706	1.00	20/20
SCHEMBL76111	1.00	20/20
SCHEMBL76378	1.00	20/20
SCHEMBL77273	1.00	20/20
SCHEMBL75828	0.92	20/20
SCHEMBL75459	0.92	20/20
SCHEMBL74593	0.78	20/20
SCHEMBL74232	0.77	20/20
SCHEMBL74550	0.77	20/20
SCHEMBL74255	0.77	20/20
SCHEMBL74330	0.77	20/20
SCHEMBL74331	0.77	20/20
SCHEMBL88026	0.77	20/20
SCHEMBL76108	0.71	20/20

Clinical trials — most relevant to MMP13 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Allogeneic Adipose Tissue-derived Mesenchymal Stem Cells in Ischemic Stroke	PHASE2	UNKNOWN
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement	PHASE1	COMPLETED
The Effect of Platelet Rich Plasma (PRP) Application on Rotator Cuff Tear.	PHASE1	COMPLETED
Matrix Metalloproteinase-1/Tissue Inhibitor of Metalloproteinase-1 (MMP-1/TIMP-1) Ratio and Diabetic Foot Ulcers	EARLY_PHASE1	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
The Biologic Basis of Hernia Formation	nan	COMPLETED
The Impact of Pregnancy and Pregnancy-associated Hypertension on Human Uterine Myometrial Artery Reactivity	nan	WITHDRAWN
Periodontal Health in Post COVID-19 Patients	nan	UNKNOWN
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar	nan	COMPLETED
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Serum COMP and MMP-3 in Knee Osteoarthritis	nan	NOT_YET_RECRUITING
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
Painful Total Knee Replacement (TKA) and I-one Therapy	nan	UNKNOWN
Efficacy of Subcutaneous Injection of Etanercept for Moderate and Severe Knee Osteoarthritis	nan	UNKNOWN
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence	nan	WITHDRAWN
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
The Effects of Sodium Fluoride and Chlorhexidine Use on Salivary IL-6 and Matrix Metalloproteinase Levels in Children With Active Caries	nan	RECRUITING
Microneedling for Dermatoporosis	nan	UNKNOWN
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development	nan	COMPLETED
The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus	nan	COMPLETED
Plasma and Scarring of Diabetic Ulcers	nan	COMPLETED
Pathology, Venous Disease, and Clinical Correlations	nan	UNKNOWN
Pelvic Organs Prolapse Treatment Using Neodymium Laser	nan	ACTIVE_NOT_RECRUITING
Efficacy of Intra-Articular Injection of Etanercept for Moderate and Severe Knee Osteoarthritis	nan	UNKNOWN
Characterizing the Inflammation Around Dental Implants: Bacterial Infection, Hypersensitivity or Both?	nan	RECRUITING
Matrix Metalloproteinases 7 and 9 in Rheumatoid Arthritis Patients With Interstitial Lung Disease	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MMP13 binder may also engage these)

Protein	Name	Similarity
O62806	—	1.000	O62806 →
O77656	—	1.000	O77656 →
O18927	—	1.000	O18927 →
P57748	—	1.000	P57748 →
P33435	—	1.000	P33435 →
Q10835	—	1.000	Q10835 →
P23097	—	1.000	P23097 →
P07152	—	0.999	P07152 →
O55123	—	0.999	O55123 →
MMP3	Stromelysin-1	0.997	landscape →
P03957	—	0.996	P03957 →
O18767	—	0.996	O18767 →
P79227	—	0.996	P79227 →
MMP1	Interstitial collagenase	0.996	landscape →
P34960	—	0.995	P34960 →
MMP20	Matrix metalloproteinase-20	0.995	landscape →
P53690	—	0.995	P53690 →
Q63341	—	0.995	Q63341 →
Q28397	—	0.995	Q28397 →
P28863	—	0.994	P28863 →
MMP10	Stromelysin-2	0.994	landscape →
O88766	—	0.994	O88766 →
MMP14	Matrix metalloproteinase-14	0.993	landscape →
Q9EPL5	—	0.993	Q9EPL5 →
P28862	—	0.993	P28862 →
O70138	—	0.992	O70138 →
P28053	—	0.992	P28053 →
P79287	—	0.992	P79287 →
Q6Y4Q5	—	0.992	Q6Y4Q5 →
Q10739	—	0.992	Q10739 →