Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483997 | 1.00 | ESR1 (0.56) | ESR1CYP19A1ESR2CES2MEN1 | |
| SCHEMBL10483990 | 1.00 | ESR1 (0.56) | ESR1CYP19A1ESR2CES2MEN1 | |
| SCHEMBL9056053 | 0.89 | CES1 (0.50) | ESR1CES2MAPTRAB9ACES1 | |
| SCHEMBL10484201 | 0.87 | CES2 (0.47) | ESR1CYP19A1ESR2CES2LMNA | |
| SCHEMBL10484187 | 0.87 | CES2 (0.47) | ESR1CYP19A1ESR2CES2LMNA | |
| SCHEMBL10484473 | 0.84 | CES1 (0.42) | ESR1CES2MEN1KMT2ALMNA | |
| SCHEMBL10484481 | 0.84 | CES1 (0.42) | ESR1CES2MEN1KMT2ALMNA | |
| SCHEMBL11711262 | 0.82 | CYP19A1 (0.41) | ESR1CYP19A1ESR2MEN1KMT2A | |
| SCHEMBL11711270 | 0.82 | CYP19A1 (0.41) | ESR1CYP19A1ESR2MEN1KMT2A | |
| SCHEMBL1151837 | 0.78 | ESR1 (0.70) | ESR1ESR2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806685-A | EXERTS VARIOUS EFFECTS ON ENDOCRINOUS SYSTEM OF RATS; INHIBITS GROWTH OF MAMMARY TUMORS | GYOGYSZERKUTATO INTEEZET/PHARMACEUTICAL RESEARCH INSTITUTE (HU) | 1989-02-21 | — | — | US | disclosed |