SCHEMBL104843

SCHEMBL104843

CC(C)(N)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL135847 0.95
SCHEMBL6281958 0.80
SCHEMBL7600038 0.80
SCHEMBL18626383 0.80
SCHEMBL19986846 0.79 LMNA (0.30)
SCHEMBL6276973 0.78
SCHEMBL2410182 0.78
Hydrochloric Acid SCHEMBL7602327 0.76
SCHEMBL3505709 0.76
Hydrochloric Acid SCHEMBL20969327 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230033510-A1 Compounds and Methods for Treatment of Visceral Pain ARENA PHARMACEUTICALS, INC. 2023-02-02 US claimed
EP-3385252-B1 CANNABINOID RECEPTOR MODULATORS ARENA PHARM INC (US) 2022-09-21 EP claimed
US-11214548-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2022-01-04 US claimed
CN-113827893-A Fire extinguishing device and method for battery compartment 国网湖南省电力有限公司 2021-12-24 CN claimed
US-20210188781-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2021-06-24 US claimed
US-20210060040-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2021-03-04 US claimed
US-10632134-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2020-04-28 US claimed
US-20200078358-A1 Compounds and Methods for Treatment of Visceral Pain ARENA PHARMACEUTICALS, INC. 2020-03-12 US claimed
CN-110709085-A Compounds and methods for treating visceral pain 艾尼纳制药公司 2020-01-17 CN claimed
US-20180354907-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2018-12-13 US claimed
US-8772300-B2 Phenyl or pyridinyl-ethynyl derivatives HOFFMANN-LA ROCHE INC. (US) 2014-07-08 US claimed
EP-2699547-A1 5-(PHENYL/PYRIDINYL-ETHINYL)-2-PYRIDINE/ 2-PYRIMIDINE-CARBORXAMIDES AS MGLUR5 MODULATORS F. Hoffmann-La Roche AG (CH) 2014-02-26 EP claimed
US-8658646-B2 Pyrrolopyrazine kinase inhibitors HOFFMANN-LAROCHE INC. (US) 2014-02-25 US claimed
WO-2012143340-A1 5-(PHENYL/PYRIDINYL-ETHINYL)-2-PYRIDINE/ 2-PYRIMIDINE-CARBORXAMIDES AS MGLUR5 MODULATORS F. HOFFMANN-LA ROCHE AG (CH) 2012-10-26 WO claimed
US-20120270852-A1 PHENYL OR PYRIDINYL-ETHYNYL DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2012-10-25 US claimed
WO-2012116278-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. (US) 2012-08-30 WO claimed
US-20120214766-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2012-08-23 US claimed
EP-0931082-A4 NODULISPORIC ACID DERIVATIVES MERCK & CO INC (US) 1999-11-17 EP claimed
EP-0931082-A1 NODULISPORIC ACID DERIVATIVES Merck &amp; Co., Inc. (a New Jersey corp.) (US) 1999-07-28 EP claimed
WO-1998012196-A1 NODULISPORIC ACID DERIVATIVES MERCK & CO., INC. (US) 1998-03-26 WO claimed