Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484384 | 1.00 | ALOX15 (0.43) | ALOX15TRPV1HIF1ACYP1A2TSHR | |
| SCHEMBL20839197 | 0.80 | ALOX15 (0.57) | ALOX15POLBCYP3A4MAPTFNTA | |
| SCHEMBL10484518 | 0.78 | ALOX15 (0.43) | ALOX15TRPV1HIF1ACYP1A2TSHR | |
| SCHEMBL10484514 | 0.78 | ALOX15 (0.43) | ALOX15TRPV1HIF1ACYP1A2TSHR | |
| SCHEMBL9702838 | 0.78 | TRPV1 (0.59) | ALOX15TRPV1ALDH1A1 | |
| SCHEMBL9702845 | 0.78 | TRPV1 (0.59) | ALOX15TRPV1ALDH1A1 | |
| SCHEMBL30883182 | 0.78 | ALOX15 (0.55) | ALOX15CYP3A4MAPTFNTAFNTB | |
| SCHEMBL254761 | 0.77 | ALOX15 (0.54) | ALOX15CYP3A4MAPTFNTAFNTB | |
| SCHEMBL8466948 | 0.77 | ALOX15 (0.54) | ALOX15CYP3A4MAPTFNTAFNTB | |
| SCHEMBL1532512 | 0.77 | HIF1A (0.42) | ALOX15TRPV1HIF1ATSHREPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4872918-A | Heterocyclic esters and smoking compositions containing a heterocyclic ester flavorant-release additive | PHILIP MORRIS INCORPORATED (US) | 1989-10-10 | — | — | US | claimed |
| US-4872918-A | Heterocyclic esters and smoking compositions containing a heterocyclic ester flavorant-release additive | PHILIP MORRIS INCORPORATED (US) | 1989-10-10 | — | — | US | disclosed |