Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.35 |
| ▸ | CCND1 | P24385 | 4/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.35 |
| ▸ | TYMS | P04818 | 2/20 | 0.35 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.35 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.33 |
| ▸ | WEE1 | P30291 | 4/20 | 0.33 |
| ▸ | PRKCA | P17252 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.33 |
| ▸ | PRKCG | P05129 | 2/20 | 0.33 |
| ▸ | PRKCB | P05771 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170829 | 0.80 | PARP1 (0.47) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL1802249 | 0.78 | CHEK1 (0.33) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL1460359 | 0.78 | PARP1 (0.40) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL14816041 | 0.78 | CDK4 (0.35) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL17023943 | 0.75 | PDE9A (0.34) | CDK4CCND1CCNE2CCNE1CDK2 | |
| Pyridine SCHEMBL913486 | 0.73 | PARP1 (0.40) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL10484680 | 0.72 | CES1 (0.45) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL2699323 | 0.70 | HSD17B10 (0.39) | PARP1MEN1KMT2AMAPT | |
| SCHEMBL5399378 | 0.70 | HSD17B10 (0.39) | PARP1MEN1KMT2AMAPT | |
| SCHEMBL10935889 | 0.69 | CDK4 (0.32) | CDK4CCND1CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4846892-A | Tetrachloroperylene-3,4,9,10-tetracarboxylic acid diimide pigment and its use | BASF AKTIENGESELLSCHAFT (DE) | 1989-07-11 | — | — | US | disclosed |