SCHEMBL1802249

SCHEMBL1802249

O=C1NC(=O)c2c3c1c(Cl)c(Cl)c1c4c(Cl)c(Cl)cc5cccc(c54)c(c4c(=O)[nH]c(=O)c24)c31

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHEK1 O14757 4/20 0.33
▸ WEE1 P30291 4/20 0.33
▸ CDK4 P11802 4/20 0.33
▸ CCND1 P24385 4/20 0.33
▸ CCNE2 O96020 3/20 0.33
▸ CCNE1 P24864 3/20 0.33
▸ CDK2 P24941 3/20 0.33
▸ CAMK2B Q13554 2/20 0.33
▸ CAMK2G Q13555 2/20 0.33
▸ CAMK2D Q13557 2/20 0.33
▸ CAMK2A Q9UQM7 2/20 0.33
▸ GUSB P08236 1/20 0.32
▸ PRKCA P17252 3/20 0.31
▸ EGFR P00533 1/20 0.31
▸ PBK Q96KB5 1/20 0.31
▸ TYMS P04818 2/20 0.30
▸ CCNB2 O95067 2/20 0.30
▸ PRKCG P05129 2/20 0.30
▸ PRKCB P05771 2/20 0.30
▸ CDK1 P06493 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10484683 0.78 CDK4 (0.35) CHEK1WEE1CDK4CCND1CCNE2
SCHEMBL10935889 0.73 CDK4 (0.32) WEE1CDK4CCND1CCNE2CCNE1
SCHEMBL14816041 0.72 CDK4 (0.35) CHEK1CDK4CCND1CCNE2CCNE1
SCHEMBL1460359 0.72 PARP1 (0.40) CHEK1CDK4CCND1CCNE2CCNE1
SCHEMBL17023943 0.69 PDE9A (0.34) CHEK1WEE1CDK4CCND1CCNE2
SCHEMBL170829 0.69 PARP1 (0.47) CHEK1WEE1CDK4CCND1CCNE2
SCHEMBL5399378 0.67 HSD17B10 (0.39) MEN1MAPTKMT2A
SCHEMBL2699323 0.67 HSD17B10 (0.39) MEN1MAPTKMT2A
SCHEMBL12748842 0.67 PPOX (0.33) —
SCHEMBL29501053 0.64 CYP1A2 (0.47) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7951938-B2 Fluorinated porphyrin dye or colorant; electrophoretic displays; high solubility, dispersibility in halogenated, perfluorinated, dielectric solvents; improved temperature latitude and switching performance especially at low temperatures SIPIX IMAGING, INC. (US) 2011-05-31 — — US disclosed
US-7473782-B2 Fluorinated dyes or colorants and their uses SIPIX IMAGING, INC. (US) 2009-01-06 — — US disclosed
US-20080173847-A1 FLUORINATED DYES OR COLORANTS AND THEIR USES E INK CALIFORNIA, LLC 2008-07-24 — — US disclosed
US-7390901-B2 Fluorinated dyes or colorants and their uses SIPIX IMAGING, INC. (US) 2008-06-24 — — US disclosed
US-20060281924-A1 Fluorinated dyes or colorants and their uses E INK CALIFORNIA, LLC 2006-12-14 — — US disclosed
EP-1664202-A2 FLUORINATED DYES OR COLORANTS AND THEIR USES Sipix Imaging, Inc. (US) 2006-06-07 — — EP disclosed
WO-2005017046-A2 FLUORINATED DYES OR COLORANTS AND THEIR USES SIPIX IMAGING, INC. (US) 2005-02-24 — — WO disclosed
US-20050039274-A1 Fluorinated dyes or colorants and their uses E INK CALIFORNIA, LLC 2005-02-24 — — US disclosed
EP-0366062-A2 Mixed crystals of pigments based on halogenated diimides of perylenetetracarboxylic acid HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-02 — — EP disclosed
US-4846892-A Tetrachloroperylene-3,4,9,10-tetracarboxylic acid diimide pigment and its use BASF AKTIENGESELLSCHAFT (DE) 1989-07-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060281924-A1 Fluorinated dyes or colorants and their uses FLNA, FLNB, CDC73 CHEK1 3936/4885WEE1 3439/4885CDK4 1089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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