SCHEMBL10485484

SCHEMBL10485484

CCCCc1cc(O)ccc1C(=O)Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.54
HTT P42858 2/20 0.47
MAPT P10636 2/20 0.47
ALOX5 P09917 2/20 0.47
MEN1 O00255 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 2/20 0.46
GAA P10253 1/20 0.46
ERAP1 Q9NZ08 1/20 0.46
KDM4E B2RXH2 1/20 0.45
HSP90AB1 P08238 1/20 0.42
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10545932 0.86 TYR (0.58) TYRHTTMAPTALOX5MEN1
SCHEMBL39293 0.85 TYR (0.56) TYRHTTMAPTALOX5MEN1
SCHEMBL19840683 0.85 TYR (0.56) TYRHTTMAPTALOX5MEN1
SCHEMBL10485919 0.85 TYR (0.56) TYRHTTMAPTALOX5MEN1
SCHEMBL27517800 0.83 TYR (0.54) TYRHTTMAPTALOX5MEN1
Hydrochloric Acid SCHEMBL10485491 0.83 TYR (0.54) TYRHTTMAPTALOX5MEN1
SCHEMBL9726272 0.83 GABRP (0.41) TYRALDH1A1GABRPGABRDGABRA1
SCHEMBL27638097 0.83 TYR (0.54) TYRHTTMAPTALOX5MEN1
SCHEMBL11466225 0.83 TYR (0.54) TYRHTTMAPTALOX5MEN1
SCHEMBL344000 0.82 TYR (0.53) TYRHTTMAPTALOX5MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102149723-A Novel glucopyranose derivatives, their preparation and their biological applications ROBERT VACHY 2011-08-10 CN claimed
JP-1193361-A None JP disclosed
CN-102149723-A Novel glucopyranose derivatives, their preparation and their biological applications ROBERT VACHY 2011-08-10 CN disclosed
CN-1942437-A Substituted azetidine compounds as cyclooxygenase-1-cyclooxygenase-2 inhibitors, and their preparation and use as medicaments ESTEVE LABOR DR (ES) 2007-04-04 CN disclosed
EP-0332761-A2 Single-functional and mixtures of multifunctional oligomeric performance additive compositions, and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-09-20 EP disclosed
JP-H01193361-A STABILIZED SYNTHETIC RESIN COMPOSITION ADEKA ARGUS CHEM CO LTD 1989-08-03 JP disclosed
US-3936479-A 2-BENZAMIDO-BENZOPHENONES, UV STABILIZERS, PLASTICS SANDOZ LTD., (SANDOZ AG) (CH) 1976-02-03 US disclosed