Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 10/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HTR7 | P34969 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10485746 | 0.90 | MEN1 (0.67) | ABCB1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10486115 | 0.89 | HTR7 (0.80) | ABCB1MAPTSMN1; SMN2HTR7KMT2A | |
| SCHEMBL10485596 | 0.89 | HTR7 (0.80) | ABCB1MAPTHTR7MEN1KMT2A | |
| SCHEMBL10485560 | 0.89 | HTR7 (0.72) | ABCB1MAPTHTR7MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10486107 | 0.89 | MEN1 (0.69) | ABCB1MAPTSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10485689 | 0.88 | HTR7 (0.78) | ABCB1MAPTHTR7KMT2A | |
| SCHEMBL10485969 | 0.87 | MEN1 (0.77) | ABCB1MAPTSMN1; SMN2HTR7MEN1 | |
| SCHEMBL10485663 | 0.87 | MEN1 (0.64) | ABCB1MAPTSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10485716 | 0.86 | MEN1 (0.65) | ABCB1MAPTSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10486062 | 0.85 | MEN1 (0.78) | ABCB1MAPTSMN1; SMN2HTR7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882330-A | 1-aryloxy-4-[((4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-11-21 | — | — | US | claimed |
| EP-0269383-A2 | 1-Aryloxy-4-[(4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-06-01 | — | — | EP | claimed |
| US-4882330-A | 1-aryloxy-4-[((4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-11-21 | — | — | US | disclosed |
| US-4806555-A | CARDIAC ARRHYTHMIA INHIBITOR | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0269383-A2 | 1-Aryloxy-4-[(4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-06-01 | — | — | EP | disclosed |