Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.66 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486300 | 0.81 | NPC1 (0.71) | NPC1HSP90AA1HSP90AB1MAPTGAA | |
| SCHEMBL3945098 | 0.80 | HSP90AA1 (1.00) | NPC1HSP90AA1HSP90AB1CDC7CCNT1 | |
| SCHEMBL12325069 | 0.78 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1MAPTALDH1A1RAB9A | |
| SCHEMBL9566485 | 0.77 | HTR2B (0.72) | NPC1HSP90AA1HSP90AB1HTR2BPDE4D | |
| SCHEMBL14055298 | 0.75 | HSP90AA1 (0.55) | NPC1HSP90AA1HSP90AB1RECQLMAPT | |
| SCHEMBL10486105 | 0.75 | HSP90AA1 (0.56) | NPC1HSP90AA1HSP90AB1HTR2BPDE4D | |
| SCHEMBL17178231 | 0.74 | HSP90AA1 (0.55) | NPC1HSP90AA1HSP90AB1CDC7CCNT1 | |
| SCHEMBL5066591 | 0.74 | NPC1 (0.62) | NPC1HSP90AA1HTR2BPDE4DSMN1; SMN2 | |
| SCHEMBL18424942 | 0.73 | HSP90AA1 (0.61) | NPC1HSP90AA1HSP90AB1MAPTPOLB | |
| SCHEMBL10822485 | 0.72 | NPC1 (0.58) | NPC1MAPTSMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873242-A | NOOTROPIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-10 | — | — | US | claimed |
| US-4873242-A | NOOTROPIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-10 | — | — | US | disclosed |