Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17349617 | 0.90 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1HTR2BPDE4DRECQL | |
| SCHEMBL17349613 | 0.84 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1HTR2BPDE4DRECQL | |
| SCHEMBL17349699 | 0.83 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1HTR2BPDE4DRECQL | |
| SCHEMBL18750344 | 0.83 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1HTR2BPDE4DRECQL | |
| SCHEMBL17349700 | 0.83 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1HTR2BPDE4DRECQL | |
| SCHEMBL17349616 | 0.81 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1HTR2BPDE4DRECQL | |
| SCHEMBL9566471 | 0.75 | RECQL (0.78) | HSP90AA1HSP90AB1HTR2BPDE4DRECQL | |
| SCHEMBL9566413 | 0.75 | HRH4 (0.66) | HSP90AA1HSP90AB1RECQLNPC1ALDH1A1 | |
| SCHEMBL10486451 | 0.75 | NPC1 (0.69) | HSP90AA1HSP90AB1HTR2BPDE4DRECQL | |
| SCHEMBL15758089 | 0.74 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1ALDH1A1AGPAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873242-A | NOOTROPIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-10 | — | — | US | claimed |
| US-4873242-A | NOOTROPIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-10 | — | — | US | disclosed |