Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 11/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486708 | 0.97 | GGPS1 (0.41) | GGPS1TSHRTHRBFDPSSMPD1 | |
| SCHEMBL10486717 | 0.97 | GGPS1 (0.41) | GGPS1TSHRTHRBFDPSSMPD1 | |
| SCHEMBL10486718 | 0.97 | GGPS1 (0.41) | GGPS1TSHRTHRBFDPSSMPD1 | |
| SCHEMBL17677263 | 0.97 | GGPS1 (0.41) | GGPS1TSHRTHRBFDPSSMPD1 | |
| SCHEMBL28919480 | 0.81 | GGPS1 (0.39) | GGPS1TSHRTHRBFDPSSMPD1 | |
| SCHEMBL18793246 | 0.79 | GGPS1 (0.38) | GGPS1TSHRTHRBFDPSSMPD1 | |
| SCHEMBL3295526 | 0.78 | TSHR (0.39) | GGPS1TSHRTHRBFDPSSMPD1 | |
| SCHEMBL1487478 | 0.78 | TSHR (0.39) | GGPS1TSHRTHRBFDPSSMPD1 | |
| SCHEMBL9682801 | 0.76 | TSHR (0.37) | GGPS1TSHRTHRBFDPSSMPD1 | |
| SCHEMBL10486695 | 0.76 | TSHR (0.44) | GGPS1TSHRTHRBFDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831096-A | VARYING THERMAL STABILITIES | PENNWALT CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| US-4604455-A | REACTING TWO PRIMARY AMINES WITH SULFURYL CHLORIDE, OXIDIZING MIXTURE OF SULFAMIDE PRODUCTS | PENNWALT CORPORATION (US) | 1986-08-05 | — | — | US | disclosed |