SCHEMBL10486708

SCHEMBL10486708

CCCCCCCCCCCC(C)(C)N=N

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GGPS1 O95749 6/20 0.41
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
FDPS P14324 9/20 0.35
SMPD1 P17405 2/20 0.34
CES2 O00748 1/20 0.34
LPAR1 Q92633 1/20 0.34
LPAR3 Q9UBY5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10486718 1.00 GGPS1 (0.41) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL10486717 1.00 GGPS1 (0.41) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL17677263 1.00 GGPS1 (0.41) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL10486707 0.97 GGPS1 (0.38) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL10486713 0.79 TSHR (0.44) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL10486685 0.79 TSHR (0.44) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL10486709 0.79 TSHR (0.44) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL10486719 0.79 TSHR (0.44) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL10486695 0.79 TSHR (0.44) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL28919480 0.79 GGPS1 (0.39) GGPS1TSHRTHRBFDPSSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4831096-A VARYING THERMAL STABILITIES PENNWALT CORPORATION (US) 1989-05-16 US disclosed
US-4604455-A REACTING TWO PRIMARY AMINES WITH SULFURYL CHLORIDE, OXIDIZING MIXTURE OF SULFAMIDE PRODUCTS PENNWALT CORPORATION (US) 1986-08-05 US disclosed