SCHEMBL10487144

SCHEMBL10487144

CC1CCCN(CC2COC3(CCC(C(C)(C)C)CC3)O2)C1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.44
HTR1A P08908 14/20 0.38
TMEM97 Q5BJF2 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
ADRA1B P35368 13/20 0.36
ADRA1A P35348 11/20 0.36
ADRA1D P25100 12/20 0.33
KDM4E B2RXH2 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8126482 0.86 GAA (0.41) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL10487109 0.86 GAA (0.56) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL10487078 0.86 GAA (0.56) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL9444079 0.83 GAA (0.51) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL10487093 0.81 GAA (0.41) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL9426648 0.81 GAA (0.42) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL9426913 0.79 GAA (0.41) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL9675637 0.77 GAA (0.42) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL9198915 0.77 GAA (0.45) GAAHTR1ATMEM97SIGMAR1ADRA1B
SCHEMBL8527748 0.74 PABPC1 (0.37) GAACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4851405-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-07-25 US claimed