PABPC1

Polyadenylate-binding protein 1 · P11940 · PABPC1 on Sugi Atlas →

54,450 patent compounds predicted against PABPC1, 35,879 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL50309 SCHEMBL50309 0.63 5/20
SCHEMBL196259 SCHEMBL196259 0.53 5/20
SCHEMBL196260 SCHEMBL196260 0.49 5/20
SCHEMBL148606 SCHEMBL148606 0.65 4/20
SCHEMBL116767 SCHEMBL116767 0.61 4/20
SCHEMBL148355 SCHEMBL148355 0.56 4/20
Benzanthrone Benzanthrone (SCHEMBL23838) 1.00 3/20
Mitonafide Mitonafide (SCHEMBL62046) 1.00 3/20
Acenaphthoquinone Acenaphthoquinone (SCHEMBL141538) 0.73 3/20
Fluoranthene Fluoranthene (SCHEMBL27152) 0.71 3/20
Fluoranthene Fluoranthene (SCHEMBL211527) 0.68 3/20
Bromide Bromide (SCHEMBL290404) 0.67 3/20
SCHEMBL55279 SCHEMBL55279 0.66 3/20
Iodide Iodide (SCHEMBL14996) 0.65 3/20
SCHEMBL187706 SCHEMBL187706 0.61 3/20
SCHEMBL254908 SCHEMBL254908 0.58 3/20
SCHEMBL26348 SCHEMBL26348 0.57 3/20
Benzo(K)Fluoranthene Benzo(K)Fluoranthene (SCHEMBL175484) 0.56 3/20
SCHEMBL138484 SCHEMBL138484 0.54 3/20
SCHEMBL57038 SCHEMBL57038 0.52 3/20

Clinical trials — most relevant to PABPC1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Study of Muscle Abnormalities in Patients With Specific Genetic Mutations nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia Intermedia nanNOT_YET_RECRUITING
Biomarkers of Cancer-Associated Myositis nanACTIVE_NOT_RECRUITING
International PPB/DICER1 Registry nanRECRUITING
B3 for NMD: Bench to Bedside and Back nanENROLLING_BY_INVITATION
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Longitudinal Study of Neurogenetic Disorders nanRECRUITING
Neurogenetics Patient Registry nanRECRUITING
Na+ Channel mRNA Regulation in Heart Failure nanCOMPLETED
Idiopathic Dilated Cardiomyopathy nanCOMPLETED
MYO-SHARE: MYO-MRI in Neuromuscular Diseases nanENROLLING_BY_INVITATION
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Mechanisms of Cell Death in Spinal Muscular Atrophy nanCOMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma nanCOMPLETED
Identification of New FTLD Genes nanUNKNOWN
Predictive Value of Maternal Blood Protein Signatures in Preterm Birth nanCOMPLETED
Characteristics of Idiopathic Familial Voice Disorders nanCOMPLETED
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Identification and Characterization of Novel Non-Coding Variants That Contribute to Genetic Disorders nanCOMPLETED
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) nanCOMPLETED
Sodium Channel Splicing in Heart Failure Trial nanCOMPLETED
The Efficiency of Postoperative Interferon-alpha Treatment in p48 Positive Patients With Hepatocellular Carcinoma nanWITHDRAWN
Genetic Investigation of Cancer Predisposition nanNOT_YET_RECRUITING
NFC Changes in SLE Patients and Its Correlation With Anti-U1RNPAntibodies and Disease Activity nanUNKNOWN
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a PABPC1 binder may also engage these)

ProteinNameSimilarity
Q5R8F7 1.000 Q5R8F7 →
Q9EPH8 1.000 Q9EPH8 →
P20965 1.000 P20965 →
Q9H361 1.000 Q9H361 →
Q6DEY7 1.000 Q6DEY7 →
P61286 1.000 P61286 →
P29341 1.000 P29341 →
Q4VXU2 1.000 Q4VXU2 →
Q6IP09 1.000 Q6IP09 →
PABPC4 Polyadenylate-binding protein 4 1.000 landscape →
Q05196 0.999 Q05196 →
P21187 0.999 P21187 →
F1QB54 0.997 F1QB54 →
Q6GR16 0.997 Q6GR16 →
Q54BM2 0.997 Q54BM2 →
Q98SP8 0.995 Q98SP8 →
P42731 0.994 P42731 →
Q6CDH3 0.994 Q6CDH3 →
A1D4K4 0.994 A1D4K4 →
Q0U1G2 0.994 Q0U1G2 →
Q2UK72 0.993 Q2UK72 →
A4QUF0 0.992 A4QUF0 →
O64380 0.992 O64380 →
A1CRM1 0.992 A1CRM1 →
Q1DXH0 0.992 Q1DXH0 →
Q4P8R9 0.992 Q4P8R9 →
Q5AI15 0.992 Q5AI15 →
A2Q848 0.991 A2Q848 →
SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0.990 landscape →
Q6FKG4 0.990 Q6FKG4 →