Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.68 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487313 | 1.00 | ABCG2 (0.68) | ABCG2GPR52ABCB1LMNASMN1; SMN2 | |
| SCHEMBL31167606 | 0.93 | ABCG2 (0.77) | ABCG2GPR52ABCB1MAOBAR | |
| Fumaric Acid SCHEMBL28398991 | 0.87 | HTT (0.66) | ABCG2GPR52LMNASMN1; SMN2NPC1 | |
| SCHEMBL4254947 | 0.83 | ABCG2 (0.90) | ABCG2GPR52ABCB1MAOBAR | |
| SCHEMBL4933303 | 0.83 | KDM4E (0.64) | ABCG2GPR52LMNASMN1; SMN2MAOB | |
| SCHEMBL4254944 | 0.83 | ABCG2 (0.90) | ABCG2GPR52ABCB1MAOBAR | |
| SCHEMBL4933294 | 0.83 | KDM4E (0.64) | ABCG2GPR52LMNASMN1; SMN2MAOB | |
| SCHEMBL11161444 | 0.82 | ABCG2 (0.68) | ABCG2GPR52ABCB1MAOBAR | |
| SCHEMBL14124754 | 0.80 | CDC25B (0.57) | ABCB1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL21678774 | 0.80 | SMN1; SMN2 (0.50) | ABCG2GPR52LMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4867737-A | ANTIULCER,-SECRETORY AND -INFLAMMATION AGENTS; GASTROINTESTINAL DISORDERS | ROUSSEL UCLAF (FR) | 1989-09-19 | — | — | US | claimed |
| US-4867737-A | ANTIULCER,-SECRETORY AND -INFLAMMATION AGENTS; GASTROINTESTINAL DISORDERS | ROUSSEL UCLAF (FR) | 1989-09-19 | — | — | US | disclosed |