Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 8/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13139841 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRCTSKTDP1CYP2D6 | |
| SCHEMBL1409773 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRCTSKTDP1CYP2D6 | |
| SCHEMBL1408967 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRCTSKTDP1CYP2D6 | |
| SCHEMBL1277511 | 0.83 | CYP1A2 (0.49) | SMN1; SMN2CTSKCA1CA2CA7 | |
| SCHEMBL1277507 | 0.83 | CYP1A2 (0.49) | SMN1; SMN2CTSKCA1CA2CA7 | |
| SCHEMBL4671387 | 0.83 | CYP2D6 (0.45) | CTSKTDP1CA1CA2CA7 | |
| SCHEMBL2104058 | 0.83 | CYP2D6 (0.45) | CTSKTDP1CA1CA2CA7 | |
| SCHEMBL4671380 | 0.83 | CYP2D6 (0.45) | CTSKTDP1CA1CA2CA7 | |
| SCHEMBL25749303 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRCTSKTDP1CA1 | |
| SCHEMBL6917401 | 0.82 | CA2 (0.41) | TSHRCTSKCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824974-A | Synthesis for the preparation of 4-amino-4,5-dihydro-2-furancarboxylic acid | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-04-25 | — | — | US | claimed |