SCHEMBL10488155

SCHEMBL10488155

Cc1ccc(S(=O)(=O)Nc2cc(Oc3ccccc3)c(N)c3c2C(=O)c2c(N)cccc2C3=O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 1/20 0.55
TRIM24 O15164 4/20 0.52
BRPF1 P55201 4/20 0.52
BRD1 O95696 3/20 0.52
NAT1 P18440 3/20 0.48
CYP2C9 P11712 3/20 0.46
CYP2C19 P33261 2/20 0.46
CYP1A2 P05177 1/20 0.46
FFAR1 O14842 1/20 0.46
PGAM1 P18669 1/20 0.45
LMNA P02545 2/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
NOD2 Q9HC29 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11599593 0.92 CDK2 (0.64) CDK2TRIM24BRPF1BRD1NAT1
SCHEMBL10780380 0.91 TRIM24 (0.60) CDK2TRIM24BRPF1BRD1CYP2C9
SCHEMBL10782037 0.91 TRIM24 (0.60) CDK2TRIM24BRPF1BRD1CYP2C9
SCHEMBL10488002 0.86 CDK2 (0.50) CDK2TRIM24BRPF1BRD1CYP2C9
SCHEMBL10777401 0.85 TRIM24 (0.54) CDK2TRIM24BRPF1BRD1CYP2C9
SCHEMBL10778237 0.85 TRIM24 (0.54) CDK2TRIM24BRPF1BRD1CYP2C9
SCHEMBL10783214 0.84 CDK2 (0.51) CDK2TRIM24BRPF1BRD1CYP2C9
SCHEMBL11775960 0.84 ADORA2A (0.54) CDK2TRIM24BRPF1BRD1NAT1
SCHEMBL18562227 0.84 CDK2 (0.60) CDK2TRIM24BRPF1BRD1CYP2C9
SCHEMBL10777447 0.83 CDK2 (0.54) CDK2TRIM24BRPF1BRD1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4863634-A LIQUID CRYSTALS BAYER AKTIENGESELLSCHAFT (DE) 1989-09-05 US disclosed
EP-0075173-A2 Anthraquinone dyes BAYER AG (DE) 1983-03-30 EP disclosed