SCHEMBL11599593

SCHEMBL11599593

Cc1ccc(S(=O)(=O)Nc2cc(Oc3ccccc3)c(N)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 1/20 0.64
TRIM24 O15164 4/20 0.57
BRPF1 P55201 4/20 0.57
BRD1 O95696 3/20 0.57
PGAM1 P18669 1/20 0.53
FFAR1 O14842 1/20 0.51
CYP2C9 P11712 3/20 0.51
CYP2C19 P33261 2/20 0.51
CYP1A2 P05177 1/20 0.51
LMNA P02545 2/20 0.50
USP2 O75604 1/20 0.50
ALDH1A1 P00352 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
NOD2 Q9HC29 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
P2RY12 Q9H244 1/20 0.49
CA12 O43570 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10780380 0.94 TRIM24 (0.60) CDK2TRIM24BRPF1BRD1PGAM1
SCHEMBL10782037 0.94 TRIM24 (0.60) CDK2TRIM24BRPF1BRD1PGAM1
SCHEMBL11775960 0.92 ADORA2A (0.54) CDK2TRIM24BRPF1BRD1PGAM1
SCHEMBL10488155 0.92 CDK2 (0.55) CDK2TRIM24BRPF1BRD1PGAM1
SCHEMBL18562227 0.92 CDK2 (0.60) CDK2TRIM24BRPF1BRD1PGAM1
SCHEMBL10777447 0.91 CDK2 (0.54) CDK2TRIM24BRPF1BRD1PGAM1
SCHEMBL11779602 0.91 CDK2 (0.54) CDK2TRIM24BRPF1BRD1PGAM1
SCHEMBL10781945 0.91 CDK2 (0.54) CDK2TRIM24BRPF1BRD1PGAM1
SCHEMBL10778237 0.88 TRIM24 (0.54) CDK2TRIM24BRPF1BRD1PGAM1
SCHEMBL10777401 0.88 TRIM24 (0.54) CDK2TRIM24BRPF1BRD1PGAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE29577-E Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1978-03-14 US disclosed
US-3963763-A Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1976-06-15 US disclosed
US-3957822-A POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed