Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethyl Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL27739494 | 0.97 | ALDH1A1 (0.70) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL9507364 | 0.95 | ALDH1A1 (0.82) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL10991977 | 0.95 | ALDH1A1 (0.82) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL9454498 | 0.95 | ALDH1A1 (0.82) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL329089 | 0.95 | ALDH1A1 (0.82) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL9665914 | 0.95 | ALDH1A1 (0.82) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL6543826 | 0.95 | ALDH1A1 (0.82) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL9495 | 0.95 | ALDH1A1 (0.82) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL10771774 | 0.95 | ALDH1A1 (0.82) | ALDH1A1LMNAHSD17B10TSHRGAA | |
| Ethyl Acetate SCHEMBL508537 | 0.95 | ALDH1A1 (0.82) | ALDH1A1LMNAHSD17B10TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100582774-C | Detection method of treating prostatitis formulation | GUIYANG YUNYAN XICHUANG PHARMACEUTICAL DEV CO LTD | 2010-01-20 | — | — | CN | disclosed |
| CN-1876028-A | Pharmaceutical preparation for treating coronary heart disease, its preparation process and quality control method | GUIYANG YUNYAN XICHUANG PHARM (CN) | 2006-12-13 | — | — | CN | disclosed |
| CN-1876050-A | Pharmaceutical preparation for treating prostatitis, its preparation process and quality control method | GUIYANG YUNYAN XICHUANG PHARM (CN) | 2006-12-13 | — | — | CN | disclosed |
| US-4855126-A | 2-ACETAMIDO-2-DEOXY-3-O-(D-GALACTOPYRANOSY)-D-GALACTO -PYRANOSIDE/ | CHEMBIOMED LTD. (CA) | 1989-08-08 | — | — | US | disclosed |
| US-4794176-A | HAPTEN DISACCHARIDE FOR CANCER DIAGNOSIS | CHEMBIOMED (CA) | 1988-12-27 | — | — | US | disclosed |
| US-4767845-A | DIAGNOSTIC FOR HUMAN CANCER; GLYCOSIDES BY REDUCTION, ACETYLATION, DEACETYLATION | CHEMBIOMED, LTD. (CA) | 1988-08-30 | — | — | US | disclosed |
| US-4362720-A | Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals | CHEMBIOMED LTD. (CA) | 1982-12-07 | — | — | US | disclosed |
| EP-0044188-A2 | Synthesis of tumor antigenic determinant | CHEMBIOMED LTD. (CA) | 1982-01-20 | — | — | EP | disclosed |
| US-4308376-A | Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals | CHEMBIOMED LTD. (CA) | 1981-12-29 | — | — | US | disclosed |
| EP-0022080-A1 | Synthetic polymer compositions containing triazine derivatives as light stabilizers and novel triazine derivatives | SANKYO COMPANY LIMITED (JP) | 1981-01-07 | — | — | EP | disclosed |
| US-4195174-A | Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals | CHEMBIOMED LTD. (CA) | 1980-03-25 | — | — | US | disclosed |