Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488639 | 0.86 | PDE4D (0.61) | PDE4DSMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL10488611 | 0.83 | SMN1; SMN2 (0.36) | PDE4DSMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL10489006 | 0.78 | PDE4D (0.67) | PDE4DSMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL10488962 | 0.77 | SMN1; SMN2 (0.68) | PDE4DSMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL10488557 | 0.74 | PDE4D (0.61) | PDE4DSMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL21172021 | 0.74 | PDE4D (0.61) | PDE4DSMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL10488604 | 0.74 | SMN1; SMN2 (0.65) | PDE4DSMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL353564 | 0.72 | PDE4D (1.00) | PDE4DSMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL10488619 | 0.72 | PDE4D (0.58) | PDE4DSMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL10488635 | 0.72 | PDE4D (0.58) | PDE4DSMN1; SMN2MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315433-A2 | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A.H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-10 | — | — | EP | claimed |
| US-4826866-A | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-02 | — | — | US | claimed |
| EP-0315433-A2 | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A.H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-10 | — | — | EP | disclosed |