Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861918 | 0.90 | TSHR (0.50) | LMNATSHRCYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8735253 | 0.84 | TSHR (0.52) | LMNATSHRCYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8736487 | 0.84 | TSHR (0.52) | LMNATSHRCYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8736615 | 0.84 | TSHR (0.52) | LMNATSHRCYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL10534570 | 0.84 | TSHR (0.52) | LMNATSHRCYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL27272549 | 0.84 | TSHR (0.52) | LMNATSHRCYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL27270393 | 0.84 | TSHR (0.52) | LMNATSHRCYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL27274533 | 0.84 | TSHR (0.52) | LMNATSHRCYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL3402007 | 0.82 | ALDH1A1 (0.57) | LMNATSHRCYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL771865 | 0.82 | CYP1A2 (0.45) | LMNATSHRCYP1A2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810778-A | OLIGOPEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |