Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754110 | 0.82 | CES1 (0.63) | MAPK1CES1CA1CA2TDP1 | |
| SCHEMBL3988785 | 0.79 | MAPK1 (0.56) | MAPK1CES1CA1CA2TDP1 | |
| SCHEMBL10489434 | 0.79 | MAPK1 (0.56) | MAPK1CES1CA1CA2TDP1 | |
| SCHEMBL6577708 | 0.77 | CES1 (0.57) | MAPK1CES1CA1CA2TDP1 | |
| SCHEMBL27765 | 0.77 | MAPK1 (1.00) | MAPK1CES1CA1CA2TDP1 | |
| SCHEMBL10489388 | 0.77 | MAPK1 (0.53) | MAPK1CES1CA1CA2TDP1 | |
| SCHEMBL10723714 | 0.76 | SRD5A2 (0.83) | MAPK1CES1CA1CA2TDP1 | |
| SCHEMBL4603989 | 0.76 | CES1 (1.00) | MAPK1CES1CA1CA2TDP1 | |
| SCHEMBL975118 | 0.76 | SRD5A2 (0.83) | MAPK1CES1CA1CA2TDP1 | |
| SCHEMBL13666983 | 0.76 | MAPK1 (0.62) | MAPK1CES1CA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833243-A | BENZOOXAZOLES OR BENZOTHIAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-23 | — | — | US | disclosed |
| US-4756741-A | Azolyloxy-carboxylic acid amide compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| US-4645525-A | Azolyoxy-carboxylic acid amide compounds and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1987-02-24 | — | — | US | disclosed |
| US-4585471-A | PREEMERGENCE | BAYER AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| US-4549899-A | Hericidally active novel substituted 3-trihalogenomethyl-1,2,4-thiadiazol-5-yl-oxyacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-29 | — | — | US | disclosed |
| US-4540430-A | Herbicidally active novel substituted 3-trichloromethyl-1,2,4-thiadiazol-5-yl-oxyacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| US-4528379-A | Preparation of substituted thiadiazolyloxyacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-09 | — | — | US | disclosed |
| US-4509971-A | Benzothiazole substituted carboxylic acid amide compounds and herbicidal methods compositions thereof | BAYER AKTIENGESELLSCHAFT (DE) | 1985-04-09 | — | — | US | disclosed |
| US-4399285-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4334073-A | BASIC CATALYSTS, DEACETYLATION, ESTERIFICATION | BAYER AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |
| EP-0005501-A2 | Heteroaryloxy-acetamides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1979-11-28 | — | — | EP | disclosed |