SCHEMBL27765

SCHEMBL27765

CC(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 1.00
LMNA P02545 2/20 0.73
MEN1 O00255 1/20 0.73
NPC1 O15118 1/20 0.73
MAPT P10636 1/20 0.73
KMT2A Q03164 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
CES1 P23141 2/20 0.68
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
TDP1 Q9NUW8 1/20 0.65
MAOB P27338 1/20 0.65
ALDH1A1 P00352 2/20 0.63
TSHR P16473 1/20 0.63
CES2 O00748 1/20 0.59
SRD5A2 P31213 1/20 0.59
GAA P10253 2/20 0.57
GSK3B P49841 1/20 0.57
POLB P06746 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL17180526 0.98 MAPK1 (0.96) MAPK1LMNAMEN1NPC1MAPT
Methyl Alcohol SCHEMBL28098714 0.98 MAPK1 (0.96) MAPK1LMNAMEN1NPC1MAPT
Bromide SCHEMBL8031021 0.98 MAPK1 (0.96) MAPK1LMNAMEN1NPC1MAPT
Acetic Acid SCHEMBL28719519 0.96 MAPK1 (0.92) MAPK1LMNAMEN1NPC1MAPT
SCHEMBL6703081 0.94 MAPK1 (0.88) MAPK1LMNAMEN1NPC1MAPT
Ethylene Glycol SCHEMBL10838204 0.92 MAPK1 (0.85) MAPK1LMNAMEN1NPC1MAPT
4-Nitrobenzoic Acid SCHEMBL27616739 0.92 MAPK1 (0.85) MAPK1LMNAMEN1NPC1MAPT
Acetohydroxamic Acid SCHEMBL28835753 0.90 MAPK1 (0.81) MAPK1LMNAMEN1NPC1MAPT
SCHEMBL27691783 0.90 MAPK1 (0.81) MAPK1LMNAMEN1NPC1MAPT
SCHEMBL40825 0.89 MAPK1 (0.79) MAPK1LMNAMEN1NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3811 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117402104-B Preparation method of chiral intermediate of atorvastatin CHONGQING MEDICAL UNIVERSITY (CN) 2026-05-26 CN claimed
CN-119955094-A Polyimide containing pyridine structure, and preparation method and application thereof 上海大学 2025-05-09 CN claimed
CN-119762911-A Natural countering patch generation method based on prompt words 北京信息科技大学 2025-04-04 CN claimed
CN-119680569-A Preparation method and hydrogenation application of hollow IrCu/C nano-catalyst 聊城大学 2025-03-25 CN claimed
CN-119318957-A For synthesizing photosensitivity catalyst for diamine compound 青岛伯川特聚科技有限公司 2025-01-17 CN claimed
CN-119241409-A Alpha-ketoamide hydrogen peroxide response precursor compound, preparation method and application 湖南工程学院 2025-01-03 CN claimed
CN-119215901-A TiO (titanium dioxide)2Modified nickel-based catalyst and method for preparing primary amine compound by using same 中南民族大学 2024-12-31 CN claimed
WO-2024260368-A1 BENZOFURAN DERIVATIVE AND PREPARATION METHOD FOR BENZOFURAN DERIVATIVE INTERMEDIATE 江苏恒瑞医药股份有限公司 2024-12-26 WO claimed
CN-119101254-A COF composite material and preparation method and application thereof 南昌大学 2024-12-10 CN claimed
CN-116535279-B Continuous and intermittent method for carbon nitride photoactivation molecular oxygen solvent-free oxidation of aromatic C-H bond 大连理工大学 2024-11-26 CN claimed
US-4267340-A BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-05-12 US claimed
US-4182892-A CHEMICAL INTERMEDIATES FOR ACYLATION OF PEPTIDES OR PENAM-RING OR CEPHAM-RING CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) 1980-01-08 US claimed
EP-0002596-A1 Method for reducing the amount of free formaldehyde in an amino formaldehyde resin BEROL KEMI AB (SE) 1979-06-27 EP claimed
US-4115643-A Process for 3-chloro cephalosporins ELI LILLY AND COMPANY (US) 1978-09-19 US claimed
US-4071681-A Process for preparing beta-lactam antibiotic substances SANKYO COMPANY LIMITED (JA) 1978-01-31 US claimed
US-4016155-A Process for preparing cephalosporin derivatives SANKYO COMPANY LIMITED (JA) 1977-04-05 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-4006092-A PEROXY COMPOUND, ALDEHYDE OR KETONE, VINYL POLYMER, BUFFER THE PROCTER & GAMBLE COMPANY (US) 1977-02-01 US claimed
US-4005029-A Laundering adjunct THE PROCTER & GAMBLE COMPANY (US) 1977-01-25 US claimed
US-3936447-A 7-Acylamino-desacetoxy-cephalosporanic acid esters and their production BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed