Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.81 |
| ▸ | PPARG | P37231 | 7/20 | 0.81 |
| ▸ | PPARD | Q03181 | 7/20 | 0.81 |
| ▸ | PPARA | Q07869 | 7/20 | 0.81 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.81 |
| ▸ | TSHR | P16473 | 4/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.81 |
| ▸ | FABP4 | P15090 | 3/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | TLR2 | O60603 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.81 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.81 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | ESR1 | P03372 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL28534845 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL1682245 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL6559646 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL9748587 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL6567029 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL25269213 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL11054069 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL15603224 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL1682224 | 0.98 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL28753435 | 0.98 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113644251-B | Hollow-structure silicon-carbon anode material and preparation method thereof | 江苏正力新能电池技术有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-113644251-A | Hollow-structure silicon-carbon negative electrode material and preparation method thereof | 东莞塔菲尔新能源科技有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-102008402-A | Nutritive and skin-care composite using stearic acids as main components and preparation method thereof | JIEDING YANG | 2011-04-13 | — | — | CN | claimed |
| CN-115777906-A | Sodium chloride nano-micron particle and preparation method and application thereof | 吉林大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-113644251-B | Hollow-structure silicon-carbon anode material and preparation method thereof | 江苏正力新能电池技术有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-113644251-A | Hollow-structure silicon-carbon negative electrode material and preparation method thereof | 东莞塔菲尔新能源科技有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-110434040-B | High-mechanical-durability super-hydrophobic/oil coating with bionic structure and preparation method thereof | 西安交通大学 | 2020-10-27 | — | — | CN | disclosed |
| EP-2995339-B1 | BALLOON CATHETER | BIOTRONIK AG (CH) | 2020-01-08 | — | — | EP | disclosed |
| US-20140216544-A1 | ELECTRICALLY CONDUCTIVE ADHESIVE, SOLAR BATTERY MODULE USING THE SAME, AND PRODUCTION METHOD THEREOF | DEXERIALS CORPORATION (JP) | 2014-08-07 | — | — | US | disclosed |
| CN-102497854-A | Pharmaceutical ophthalmological liquid compositions containing propionic acid derivatives as a preservative | ALLERGAN INC | 2012-06-13 | — | — | CN | disclosed |
| CN-102008402-A | Nutritive and skin-care composite using stearic acids as main components and preparation method thereof | JIEDING YANG | 2011-04-13 | — | — | CN | disclosed |
| CN-101631565-A | Cyclodextrin formulations | DEVIREX AG | 2010-01-20 | — | — | CN | disclosed |
| CN-1138515-C | Dispersions comprising oil-based biliquid foam and aqueous gel | — | 2004-02-18 | — | — | CN | disclosed |
| CN-1218386-A | Dispersions comprising oil-based biliquid foam and aqueous gel | DISPERSE TECHNOLOGIES LTD (GB) | 1999-06-02 | — | — | CN | disclosed |
| CN-1040835-A | The fabric sofetening composition that contains getting imidazoline ester and quaternized ester-ammonium salt mixture | PROCTER & GAMBLE (US) | 1990-03-28 | — | — | CN | disclosed |
| EP-0345842-A2 | Fabric softening compositions containing mixtures of substituted imidazoline esters and quartenized ester-ammonium salts | THE PROCTER & GAMBLE COMPANY (US) | 1989-12-13 | — | — | EP | disclosed |
| EP-0330261-A2 | Stable biodegradable fabric softening compositions containing 2-hydroxypropyl monoester quaternized ammonium salts | THE PROCTER & GAMBLE COMPANY (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4840738-A | ANTISTATIC AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1989-06-20 | — | — | US | disclosed |