Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174591 | 0.76 | ELANE (0.59) | ELANEALDH1A1MAPTLMNARAB9A | |
| SCHEMBL6503868 | 0.76 | ELANE (0.71) | ELANEMAPTCTRB1 | |
| SCHEMBL10657051 | 0.75 | ELANE (1.00) | ELANECTRB1 | |
| SCHEMBL10662669 | 0.72 | ELANE (0.73) | ELANECTRB1 | |
| SCHEMBL10489711 | 0.71 | ELANE (1.00) | ELANE | |
| SCHEMBL31448160 | 0.70 | HSPB1 (0.53) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL10662992 | 0.69 | ELANE (0.63) | ELANEALDH1A1MAPT | |
| SCHEMBL10489757 | 0.69 | ELANE (0.66) | ELANE | |
| SCHEMBL10489670 | 0.69 | ELANE (0.66) | ELANE | |
| SCHEMBL10489879 | 0.69 | ELANE (0.69) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873232-A | ARTHRITIS AND AUTOIMMUNE DISEASES | SYNTEX (US) | 1989-10-10 | — | — | US | disclosed |