SCHEMBL10490002

SCHEMBL10490002

CC(C)OC(=O)CNC(=O)[C@H](CS)NC(=O)CC[C@H](N)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.71
GSTK1 Q9Y2Q3 1/20 0.71
GLO1 Q04760 2/20 0.51
NOD1 Q9Y239 10/20 0.43
FNTA P49354 2/20 0.39
FNTB P49356 2/20 0.39
PGGT1B P53609 1/20 0.39
FOLH1 Q04609 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL680549 1.00 PTGS1 (0.71) PTGS1GSTK1GLO1NOD1FNTA
Ethylene Glycol SCHEMBL3625093 0.97 PTGS1 (0.67) PTGS1GSTK1GLO1NOD1FNTA
Sulfuric Acid SCHEMBL7496979 0.96 PTGS1 (0.65) PTGS1GSTK1GLO1NOD1FNTA
Sulfuric Acid SCHEMBL7504984 0.96 PTGS1 (0.65) PTGS1GSTK1GLO1NOD1FNTA
SCHEMBL26945939 0.92 PTGS1 (0.67) PTGS1GSTK1GLO1NOD1FNTA
SCHEMBL6064367 0.92 PTGS1 (0.70) PTGS1GSTK1GLO1NOD1FNTA
SCHEMBL19293541 0.92 PTGS1 (0.59) PTGS1GSTK1GLO1NOD1FNTA
SCHEMBL6658547 0.91 PTGS1 (0.57) PTGS1GSTK1GLO1NOD1FNTA
SCHEMBL24359832 0.90 PTGS1 (0.67) PTGS1GSTK1GLO1NOD1FNTA
SCHEMBL14842415 0.90 PTGS1 (0.67) PTGS1GSTK1GLO1NOD1FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3270889-B1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES MIRECA MEDICINES GMBH (DE) 2024-02-07 EP claimed
WO-2022074181-A1 NANOCARRIER FORMULATIONS FOR INHALATION EnhanX Biopharm Inc. (TW) 2022-04-14 WO claimed
EP-3395372-B1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM ENHANX BIOPHARM INC (TW) 2022-04-06 EP claimed
EP-3194027-B1 COMPOSITIONS FOR USE IN TREATING PSYCHOTIC DISORDERS SOUND PHARMACEUTICALS INCORPORATED (US) 2026-02-11 EP disclosed
US-12427138-B2 Treatment of Meniere's disease SOUND PHARMACEUTICALS INCORPORATED (US) 2025-09-30 US disclosed
EP-4461360-A2 TREATMENT OF MENIERE'S DISEASE Sound Pharmaceuticals Incorporated (US) 2024-11-13 EP disclosed
EP-3458045-B1 EBSELEN FOR USE IN THE TREATMENT OF MENIERE'S DISEASE SOUND PHARMACEUTICALS INCORPORATED (US) 2024-08-21 EP disclosed
US-20240050409-A1 Methods and Compositions for Treating Psychotic Disorders SOUND PHARMACEUTICALS INCORPORATED 2024-02-15 US disclosed
EP-3270889-B1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES MIRECA MEDICINES GMBH (DE) 2024-02-07 EP disclosed
WO-2022074181-A1 NANOCARRIER FORMULATIONS FOR INHALATION EnhanX Biopharm Inc. (TW) 2022-04-14 WO disclosed
EP-3395372-B1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM ENHANX BIOPHARM INC (TW) 2022-04-06 EP disclosed
US-20210379017-A1 Methods and Compositions for Treating Psychotic Disorders SOUND PHARMACEUTICALS INCORPORATED 2021-12-09 US disclosed
WO-2017201318-A1 TREATMENT OF MENIERE'S DISEASE SOUND PHARMACEUTICALS INCORPORATED (US) 2017-11-23 WO disclosed
US-20170246148-A1 Methods and Compositions for Treating Psychotic Disorders SOUND PHARMACEUTICALS INCORPORATED 2017-08-31 US disclosed
US-4879370-A ALKYL ESTER TO INCREASE CELLULAR LEVELS CORNELL RESEARCH FOUNDATION, INC. (US) 1989-11-07 US disclosed
US-4784685-A MONOALKYL ESTERS OF GLUTATHIONE TO YIELD GLUTATHIONE CORNELL RESEARCH FOUNDATION, INC. (US) 1988-11-15 US disclosed
US-4710489-A ADMINISTERING PURE ALKYL MONOESTERS OF GLUTATHIONE; IN VIVO HYDROLYSIS CORNELL RESEARCH FOUNDATION, INC. (US) 1987-12-01 US disclosed
US-4709013-A ESTERIFICATION, SALT FORMATION YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1987-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210379017-A1 Methods and Compositions for Treating Psychotic Disorders GPX4, GPX1, GSR PTGS1 242/4885GSTK1 15/4885GLO1 184/4885
US-12427138-B2 Treatment of Meniere's disease GPX1, GSR, GPX4 PTGS1 77/4885GSTK1 58/4885GLO1 390/4885
US-20240050409-A1 Methods and Compositions for Treating Psychotic Disorders GPX4, GPX1, GSR PTGS1 242/4885GSTK1 15/4885GLO1 184/4885
US-20170246148-A1 Methods and Compositions for Treating Psychotic Disorders GPX4, GPX1, GSR PTGS1 235/4885GSTK1 14/4885GLO1 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.