Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5639931 | 0.80 | GAA (0.46) | GAAATMLMNASMN1; SMN2MGAM | |
| SCHEMBL6438119 | 0.76 | NPSR1 (0.32) | — | |
| SCHEMBL27579507 | 0.75 | GAA (0.42) | GAASMN1; SMN2MGAMSIMGAM2 | |
| SCHEMBL16000680 | 0.75 | GAA (0.42) | GAAATMLMNASMN1; SMN2MGAM | |
| SCHEMBL530162 | 0.74 | GAA (0.42) | GAAATMLMNASMN1; SMN2MGAM | |
| SCHEMBL8694565 | 0.74 | ALDH1A1 (0.32) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL5138578 | 0.73 | GAA (0.46) | GAAATMLMNASMN1; SMN2MGAM | |
| SCHEMBL28525263 | 0.72 | GAA (0.40) | GAAATMLMNASMN1; SMN2MGAM | |
| SCHEMBL28458948 | 0.72 | GAA (0.40) | GAASMN1; SMN2MGAMSIMGAM2 | |
| SCHEMBL35709 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4709016-A | Molecular analytical release tags and their use in chemical analysis | NORTHEASTERN UNIVERSITY (US) | 1987-11-24 | — | — | US | claimed |
| US-4650750-A | Method of chemical analysis employing molecular release tag compounds | GIESE ROGER W (US) | 1987-03-17 | — | — | US | claimed |
| US-4859795-A | Ethylenically unsaturated phosphinic acid and thiophosphinic acid isocyanates and isothiocyanates, and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |
| EP-0244747-A2 | Ethylenically unsaturated phosphinic acid or thiophosphinic acid isocyanates or isothiocyanates and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-11 | — | — | EP | disclosed |