Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8677240 | 0.83 | POLB (0.70) | POLBL3MBTL1KMT2AGAAMAPT | |
| SCHEMBL3988102 | 0.78 | KMT2A (0.64) | L3MBTL1KMT2AGAAMAPTHPGD | |
| SCHEMBL18003534 | 0.77 | POLB (0.70) | POLBL3MBTL1KMT2AGAAMAPT | |
| SCHEMBL4822785 | 0.75 | GSK3B (0.84) | POLBL3MBTL1KMT2AGAAMAPT | |
| SCHEMBL7504407 | 0.74 | GAA (1.00) | POLBL3MBTL1KMT2AGAAMAPT | |
| SCHEMBL14508422 | 0.74 | MAPT (0.64) | POLBL3MBTL1KMT2AGAAMAPT | |
| SCHEMBL8677047 | 0.73 | MAPT (0.58) | POLBL3MBTL1KMT2AGAAMAPT | |
| SCHEMBL28325219 | 0.73 | POLB (0.64) | POLBL3MBTL1KMT2AGAAMAPT | |
| SCHEMBL29310490 | 0.72 | GSK3B (0.79) | POLBL3MBTL1KMT2AGAAMAPT | |
| SCHEMBL21985337 | 0.71 | MAPT (0.60) | POLBL3MBTL1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4859670-A | 2-Azolylmethyl-2-aryl-1,3-dioxolanes and the salts thereof, agents containing same, and the use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |
| EP-0237962-A2 | 2-Azolylmethyl-2-aryl-1,3-dioxolanes and their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |