Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10786663 | 1.00 | TSHR (0.52) | TSHRKCNH2CNR2NPC1JAK2 | |
| SCHEMBL7104914 | 1.00 | TSHR (0.52) | TSHRKCNH2CNR2NPC1JAK2 | |
| SCHEMBL10490489 | 1.00 | TSHR (0.52) | TSHRKCNH2CNR2NPC1JAK2 | |
| SCHEMBL27372199 | 1.00 | TSHR (0.52) | TSHRKCNH2CNR2NPC1JAK2 | |
| SCHEMBL8065394 | 1.00 | TSHR (0.52) | TSHRKCNH2CNR2NPC1JAK2 | |
| SCHEMBL21917084 | 1.00 | TSHR (0.52) | TSHRKCNH2CNR2NPC1JAK2 | |
| SCHEMBL16294617 | 1.00 | TSHR (0.52) | TSHRKCNH2CNR2NPC1JAK2 | |
| SCHEMBL4342408 | 1.00 | TSHR (0.52) | TSHRKCNH2CNR2NPC1JAK2 | |
| Hydrochloric Acid SCHEMBL11408583 | 0.98 | KCNH2 (0.50) | TSHRKCNH2CNR2NPC1JAK2 | |
| Hydrochloric Acid SCHEMBL11405509 | 0.98 | KCNH2 (0.50) | TSHRKCNH2CNR2NPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4804747-A | NON-LINEAR OPTICAL ELEMENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-14 | — | — | US | disclosed |
| EP-0293093-A2 | Azo Compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-11-30 | — | — | EP | disclosed |
| EP-0220042-A2 | Azo compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-29 | — | — | EP | disclosed |