SCHEMBL7104914

SCHEMBL7104914

CCCCCCCCCCCCN(CC)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
KCNH2 Q12809 6/20 0.51
CNR2 P34972 4/20 0.51
NPC1 O15118 1/20 0.50
JAK2 O60674 1/20 0.50
RAB9A P51151 1/20 0.50
PAX8 Q06710 1/20 0.50
ICMT O60725 1/20 0.44
ALB P02768 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
HTR7 P34969 1/20 0.42
TACR1 P25103 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10786663 1.00 TSHR (0.52) TSHRKCNH2CNR2NPC1JAK2
SCHEMBL10490489 1.00 TSHR (0.52) TSHRKCNH2CNR2NPC1JAK2
SCHEMBL27372199 1.00 TSHR (0.52) TSHRKCNH2CNR2NPC1JAK2
SCHEMBL8065394 1.00 TSHR (0.52) TSHRKCNH2CNR2NPC1JAK2
SCHEMBL21917084 1.00 TSHR (0.52) TSHRKCNH2CNR2NPC1JAK2
SCHEMBL16294617 1.00 TSHR (0.52) TSHRKCNH2CNR2NPC1JAK2
SCHEMBL10490441 1.00 TSHR (0.52) TSHRKCNH2CNR2NPC1JAK2
SCHEMBL4342408 1.00 TSHR (0.52) TSHRKCNH2CNR2NPC1JAK2
Hydrochloric Acid SCHEMBL11408583 0.98 KCNH2 (0.50) TSHRKCNH2CNR2NPC1JAK2
Hydrochloric Acid SCHEMBL11405509 0.98 KCNH2 (0.50) TSHRKCNH2CNR2NPC1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4562253-A Deacylation of amides BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 1985-12-31 US claimed
US-4254092-A Method for separating hydrogen chloride and hydrogen bromide CHEMISCHE WERKE HULS AG (DE) 1981-03-03 US claimed
EP-1280600-A2 SUPPORTED CATALYST SYSTEM COMPRISING A METALLOCENE, A LEWIS-BASE AND AN ORGANODEMENTAL COMPOUND OF MAIN GROUP III, AND ITS USE Basell Polypropylen GmbH (DE) 2003-02-05 EP disclosed
WO-2001047635-A2 SUPPORTED CATALYST SYSTEM CONTAINING A METALLOCENE, A LEWIS BASE AND AN ELEMENTALLY ORGANIC COMPOUND OF MAIN GROUP III AND THE USE THEREOF BASELL POLYPROPYLEN GMBH (DE) 2001-07-05 WO disclosed
US-5308735-A Aromatic-aldehyde resins, improved solubility NIPPON PAINT CO., LTD. (JP) 1994-05-03 US disclosed
EP-0540016-A1 Photosensitive resin and resin composition for lithographic printing Nippon Paint Co., Ltd. (JP) 1993-05-05 EP disclosed
US-4804747-A NON-LINEAR OPTICAL ELEMENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-02-14 US disclosed
EP-0293093-A2 Azo Compound IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-11-30 EP disclosed
EP-0220042-A2 Azo compound IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-29 EP disclosed
EP-0108034-B1 DEACYLATION OF AMIDES BIOCHEMIE Gesellschaft m.b.H. (AT) 1987-01-28 EP disclosed
US-4562253-A Deacylation of amides BIOCHEMIE GESELLSCHAFT M.B.H. (AT) 1985-12-31 US disclosed
EP-0003472-B1 PROCESS FOR SEPARATING HYDROGEN CHLORIDE FROM SOLUTIONS OF AMINO-HYDROCHLORIDES CHEMISCHE WERKE HÜLS AG (DE) 1981-09-16 EP disclosed
EP-0008330-B1 PROCESS FOR THE SEPARATION OF HYDROGEN CHLORIDE AND HYDROGEN BROMINE CHEMISCHE WERKE HÜLS AG (DE) 1981-05-20 EP disclosed
EP-0027508-A1 Process for preparing ammonia and hydrogen chloride from ammonium chloride CHEMISCHE WERKE HÜLS AG (DE) 1981-04-29 EP disclosed
US-4254092-A Method for separating hydrogen chloride and hydrogen bromide CHEMISCHE WERKE HULS AG (DE) 1981-03-03 US disclosed
EP-0008330-A1 Process for the separation of hydrogen chloride and hydrogen bromine CHEMISCHE WERKE HÜLS AG (DE) 1980-03-05 EP disclosed
EP-0003472-A2 Process for separating hydrogen chloride from solutions of amino-hydrochlorides CHEMISCHE WERKE HÜLS AG (DE) 1979-08-22 EP disclosed
US-4115530-A EXTRACTION WITH AMINES CHEMISCHE WERKE HULS AG (DE) 1978-09-19 US disclosed
US-4045458-A FRIEDEL-CRAFTS CATALYSTS KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1977-08-30 US disclosed
US-3930671-A Color former and pressure-sensitive copying paper FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed