Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10490876 | 0.84 | HTR2A (0.67) | HTR2ARAB9AAKR1C3MAOBHTT | |
| SCHEMBL10490891 | 0.83 | KMT2A (0.50) | HTTMAPTNPSR1L3MBTL1 | |
| SCHEMBL5827968 | 0.82 | HTR2A (0.80) | HTR2ARAB9AAKR1C3MAOBHTT | |
| SCHEMBL23042226 | 0.82 | HTR2A (0.67) | HTR2ARAB9AAKR1C3MAOBIDO1 | |
| SCHEMBL29074496 | 0.81 | MAPT (0.58) | RAB9AAKR1C3MAOBMAOAMAPT | |
| SCHEMBL10490867 | 0.81 | HTR2A (0.53) | HTR2ARAB9AAKR1C3MAOBHTT | |
| SCHEMBL5719541 | 0.80 | HTT (0.56) | RAB9AAKR1C3MAOBMAOAHTT | |
| SCHEMBL14621621 | 0.79 | HTR2A (0.74) | HTR2ARAB9AAKR1C3MAOBHTT | |
| SCHEMBL1714950 | 0.79 | HTR2A (0.70) | HTR2ARAB9AHTTMAPT | |
| Water SCHEMBL10938437 | 0.78 | HTR2A (0.73) | HTR2ARAB9AMAOBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219926-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-04-29 | — | — | EP | claimed |
| US-4835150-A | ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1989-05-30 | — | — | US | disclosed |
| EP-0308559-A2 | Cephalosporins, process for their preparation, pharmaceutical compositions containing them and intermediates | BEECHAM GROUP PLC (GB) | 1989-03-29 | — | — | EP | disclosed |
| EP-0265185-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | disclosed |
| EP-0219926-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-04-29 | — | — | EP | disclosed |