Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YARS1 | P54577 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | BLM | P54132 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | THPO | P40225 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10490800 | 0.99 | YARS1 (0.42) | YARS1MAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10817167 | 0.91 | TDP1 (0.40) | YARS1MAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11582652 | 0.90 | POLB (0.41) | YARS1MAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10770220 | 0.90 | MAPT (0.36) | YARS1MAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL10404206 | 0.90 | MAPT (0.36) | YARS1MAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL9327248 | 0.87 | MAPT (0.46) | YARS1MAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL9567734 | 0.87 | MAPT (0.46) | YARS1MAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL11431737 | 0.87 | MAPT (0.46) | YARS1MAPTPDE3ASLC22A6SLC22A8 | |
| SCHEMBL7828421 | 0.84 | ATM (0.42) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL8597022 | 0.84 | ATM (0.42) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4877783-A | β-lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1989-10-31 | — | — | US | disclosed |
| US-4835150-A | ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1989-05-30 | — | — | US | disclosed |
| EP-0308559-A2 | Cephalosporins, process for their preparation, pharmaceutical compositions containing them and intermediates | BEECHAM GROUP PLC (GB) | 1989-03-29 | — | — | EP | disclosed |
| EP-0071395-B1 | BETA-LACTAM ANTIBACTERIAL AGENTS | BEECHAM GROUP PLC (GB) | 1988-08-10 | — | — | EP | disclosed |
| EP-0233173-A1 | 1-[3-(2-Hydroxy-3-alkylamino-propoxy)-2-thienyl]-3-phenyl-1-propanones and their acid addition salts, process for their preparation and pharmaceutical compositions containing them | Laevosan-Gesellschaft m.b.H. (AT) | 1987-08-19 | — | — | EP | disclosed |
| EP-0093564-B1 | BETA-LACTAM ANTIBIOTICS | BEECHAM GROUP PLC (GB) | 1987-06-24 | — | — | EP | disclosed |
| EP-0219926-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-04-29 | — | — | EP | disclosed |
| US-4609652-A | FORMAMIDYL DERIVATIVES OF AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1986-09-02 | — | — | US | disclosed |
| US-4540688-A | β-Lactam antibiotics | BEECHAM GROUP P.L.C. (GB) | 1985-09-10 | — | — | US | disclosed |
| US-4539149-A | β-Lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1985-09-03 | — | — | US | disclosed |
| EP-0131611-A1 | $g(b)-LACTAM ANTIBACTERIAL AGENTS | BEECHAM GROUP PLC (GB) | 1985-01-23 | — | — | EP | disclosed |
| WO-1984002911-A1 | beta-LACTAM ANTIBACTERIAL AGENTS | BEECHAM GROUP PLC (GB) | 1984-08-02 | — | — | WO | disclosed |
| EP-0071395-A1 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1983-02-09 | — | — | EP | disclosed |