Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 14/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219749 | 0.70 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL29107867 | 0.70 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL160611 | 0.69 | CYP11B1 (0.69) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL10492247 | 0.69 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL1024261 | 0.69 | CYP11B1 (0.84) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL13907297 | 0.68 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL13105237 | 0.68 | CYP11B1 (0.72) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL21415903 | 0.68 | CYP11B1 (0.48) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| Hydrochloric Acid SCHEMBL1775141 | 0.67 | CYP11B1 (0.81) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL28750656 | 0.67 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831045-A | Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| US-4791126-A | Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredients | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-12-13 | — | — | US | disclosed |
| EP-0047109-B1 | RHODANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND ALDOSE REDUCTASE INHIBITOR CONTAINING THE RHODANINE DERIVATIVES AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1985-01-02 | — | — | EP | disclosed |