Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 17/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 15/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | QPCT | Q16769 | 1/20 | 0.53 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.53 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1532637 | 0.77 | TSHR (0.47) | POLBMAPT | |
| SCHEMBL16516757 | 0.75 | SMN1; SMN2 (0.57) | CYP1A2CYP2D6MAPTTBXAS1QPCT | |
| SCHEMBL10929720 | 0.75 | AGER (0.48) | CYP19A1POLB | |
| SCHEMBL2105200 | 0.74 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL21415903 | 0.73 | CYP11B1 (0.48) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL16523578 | 0.73 | MEN1 (0.46) | CYP19A1CYP1A2POLBCYP3A4CYP2D6 | |
| SCHEMBL29107867 | 0.71 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL15179016 | 0.71 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL30523908 | 0.71 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL30523909 | 0.71 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1117090-C | N-acyl-2-substituted-4-(benzimidazolyl-or imidazopyridinyl-substituted pesidues)-piperidines as tachykinin antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2003-08-06 | — | — | CN | disclosed |
| CN-1206414-A | N-acyl-2-substituted-4- (benzimidazolyl-or imidazopyridinyl-substituted residues) piperidines as tachykinin antagonists | JANSSEN PHARMACEUTICA NV (BE) | 1999-01-27 | — | — | CN | disclosed |
| EP-0492178-B1 | Naphthoic acid derivative | FUJIREBIO KK (JP) | 1995-10-04 | — | — | EP | disclosed |
| US-5324728-A | Lipoxygenase inhibiting antiallergens | FUJIREBIO INC. (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0492178-A2 | Naphthoic acid derivative | FUJIREBIO INC. (JP) | 1992-07-01 | — | — | EP | disclosed |
| US-4528195-A | Imidazole derivatives and salts thereof, their synthesis and intermediates and pharmaceutical formulations | THOROGOOD PETER B (GB) | 1985-07-09 | — | — | US | disclosed |
| EP-0003560-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-02 | — | — | EP | disclosed |
| US-4416895-A | ANTICOAGULANTS, ANTISHOCK AGENTS | BURROUGHS WELLCOME CO. (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0003560-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |