Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.40 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1049635 | 0.91 | ZAP70 (0.53) | ZAP70CLK4EGFRAURKATTBK1 | |
| SCHEMBL1047814 | 0.87 | CYP3A4 (0.45) | NUDT1ZAP70CYP1A2CYP3A4LMNA | |
| SCHEMBL1048999 | 0.84 | ZAP70 (0.49) | ZAP70CLK4EGFRAURKATTBK1 | |
| SCHEMBL1048512 | 0.83 | ZAP70 (0.47) | ZAP70LMNAEGFRTTBK1TTBK2 | |
| SCHEMBL1045599 | 0.83 | ZAP70 (0.47) | ZAP70CLK4EGFRAURKATTBK1 | |
| SCHEMBL1048942 | 0.83 | ZAP70 (0.48) | ZAP70LMNAALDH1A1TTBK1TTBK2 | |
| SCHEMBL1043299 | 0.83 | JAK2 (0.49) | ZAP70TTBK1TTBK2JAK2FGFR1 | |
| SCHEMBL27806170 | 0.83 | ZAP70 (0.51) | ZAP70CYP1A2CYP3A4LMNACLK4 | |
| SCHEMBL1049370 | 0.82 | ZAP70 (0.46) | NUDT1ZAP70CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL1045523 | 0.82 | JAK2 (0.49) | ZAP70CLK4TTBK1TTBK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546370-B2 | Compounds and compositions as kinase inhibitors | IRM LLC (BM) | 2013-10-01 | — | — | US | claimed |
| US-20110003798-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2011-01-06 | — | — | US | claimed |
| CN-101990539-A | Compounds and compositions as kinase inhibitors | IRM LLC | 2011-03-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003798-A1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | FYN, SYK, RET | NUDT1 3348/4885ZAP70 4/4885CYP1A2 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.